小肠结肠炎耶氏菌分布广泛,除人外,常常存在于许多家畜、家禽、野生动物、食物和周围环境中。但这些分离物大量是无毒力的,故鉴定菌株的毒力对于瞭解小肠结肠炎耶氏菌病流行有十分重要意义。我们将小肠结肠炎耶氏菌毒力株R34+(0:3血清型)、P6+(O:3血清型)和Y15+(0:9血清型)多次免疫家兔,制备免疫血清,经用各自去毒力的衍生株充分吸收后,获得毒力因子血 Yersinia enterocolitica is widely distributed and often exists in many domestic animals, poultry, wildlife, food and the environment, except humans. However, a large number of these isolates are non-virulent, the virulence of the identified strains is of great importance for understanding the epidemic of the enterocolitis of Yersinia enterocolitica. We immunized rabbits multiple times with the Y. enteritidis virulence strains R34 + (0: 3 serotype), P6 + (O: 3 serotypes) and Y15 + (0: 9 serotypes) After the virulent derivative strain is fully absorbed, the virulence factor blood is obtained