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目的:探讨嗜铬细胞瘤的临床特点、诊断方法、治疗及预后。方法:对45例经手术及病理确诊的嗜铬细胞瘤进行分析。结果:嗜铬细胞瘤临床表现复杂多样,但交感神经兴奋及高代谢症群仍为主要表现(血压升高75.6％,心悸73.3％,头痛68.9％,多汗66.7％,消瘦57.8％);结合临床、实验室及影像学检查,术前确诊率达95.6％;多种诊断手段相互配合对明确不典型病例肿瘤所在部位有实用价值;经用苯苄胺做充分术前准备,术中、术后无1例发生并发症。结论:早期采用有效手段发现肿瘤,积极有效控制血压及症状,尽早手术,可改善患者生存质量。
Objective: To investigate the clinical features, diagnostic methods, treatment and prognosis of pheochromocytoma. Methods: 45 cases of pheochromocytoma confirmed by surgery and pathology were analyzed. Results: The clinical manifestations of pheochromocytoma were complex and diverse, but sympathetic nerve stimulation and hypermetabolism group were still the main performance (75.6% blood pressure, 73.3% palpitation, 68.9% headache, 66.7% hyperhidrosis, 57.8% weight loss); Clinical, laboratory and imaging examinations, with a preoperative diagnosis rate of 95.6%; a variety of diagnostic methods have practical value in clarifying the location of the tumor in atypical cases; full preoperative preparation with phenylbenzylamine, intraoperative, and surgery None of the complications occurred afterwards. Conclusion: The early use of effective means to find tumors, active and effective control of blood pressure and symptoms, and early surgery can improve the quality of life of patients.