本文观察了在体外温育条件下Ca~(2+)对大鼠和豚鼠肺泡巨噬细胞吞噬能力的影响。结果表明大鼠和豚鼠的正常吞噬能力无明显差异,Ca~(2+)可增加大鼠和豚鼠肺泡巨噬细胞的吞噬能力。三氟啦嗪和酚妥胺阻断Ca~(2+)受体蛋白——钙调素之后,Ca~(2+)对肺泡巨噬细胞吞噬能力的增强作用不再出现,说明Ca~(2+)的这种作用可能是通过细胞内钙调素来实现的。 This article investigates the effects of Ca ~ (2+) on the phagocytic capacity of alveolar macrophages in rats and guinea pigs incubated in vitro. The results showed that there was no significant difference in normal phagocytosis between rats and guinea pigs. Ca ~ (2+) increased the phagocytic capacity of alveolar macrophages in rats and guinea pigs. After the trimethoprim and phenytoin blocked the Ca 2+ receptor protein calmodulin, the enhancement effect of Ca 2+ on the phagocytosis of alveolar macrophages no longer appeared, indicating that Ca 2+ 2+) this effect may be achieved by intracellular calmodulin.