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钩吻是毒性极强的外用中药,应用不当或误服可致中毒,有时还可致命。主要毒性成分是钩吻碱,以钩吻素子含量最高。钩吻中毒主要抑制延髓呼吸中枢,并抑制脑和脊髓的运动中枢。临床表现以呼吸系统、神经系统症状为主,可出现呼吸衰竭和呼吸肌麻痹,是钩吻中毒最常见的死因。目前尚无特效解毒剂,以对症支持治疗为主。洗胃时须注意监测呼吸情况,必要时先行气管插管再洗胃。
Kiss Kiss is a highly toxic topical Chinese medicine, improper application or may result in poisoning, and sometimes fatal. The main toxic component is carboplatin, which has the highest content of koumissin. Kiss kiss poisoning mainly inhibit the medullary respiratory center and inhibit the brain and spinal motor center. Clinical manifestations of the respiratory system, neurological symptoms, respiratory failure and respiratory muscle paralysis may occur, is the most common cause of kiss kisses. There is no effective antidote to symptomatic and supportive treatment. Gastric lavage should pay attention to monitoring of respiratory conditions, if necessary, first tracheal intubation and then gastric lavage.