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目的采用多普勒导丝评价心脏X综合征(CSX)患者的冠脉循环。方法采用多普勒导丝测定观察组(38例CSX患者)及对照组(12例健康对照)的冠脉循环生理学参数。结果观察组的冠脉血流储备(CFR)为1.83±0.21,明显低于对照组的2.67±0.28,差异具有统计学意义(P<0.05);观察组的微血管阻力指数(IMR)为(36.2±5.3)U,明显高于对照组的(21.2±4.7)U,差异具有统计学意义(P<0.05);两组的血流储备分数(FFR)比较差异无统计学意义(0.92±0.08 vs 0.94±0.06,P>0.05)。结论 CSX患者心肌微血管阻力增加导致冠脉血流储备功能障碍。
Objective To evaluate the coronary circulation in patients with cardiac X syndrome using Doppler guidewire. Methods The coronary circulation physiological parameters of the observation group (38 CSX patients) and the control group (12 healthy controls) were determined by Doppler guided wire. Results The coronary flow reserve (CFR) in the observation group was 1.83 ± 0.21, which was significantly lower than that in the control group (2.67 ± 0.28, P <0.05). The IMR of the observation group was (36.2 ± 5.3) U, which was significantly higher than that of the control group (21.2 ± 4.7) U, the difference was statistically significant (P <0.05). There was no significant difference in FFR between the two groups (0.92 ± 0.08 vs 0.94 ± 0.06, P> 0.05). Conclusions Increased myocardial microvascular resistance in patients with CSX leads to coronary blood flow reserve dysfunction.