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近20年来对乙肝病毒(HBV)与肝癌发病机理的研究取得了长足发展。普遍认为HBV慢性感染与原发性肝癌的发生有密切关系。并在流行病学、免疫病理学及分子病理学等方面得到证实。近几年来对丙型肝炎(HCV)或HBV与HCV同时或分别感染与肝癌发病机理的研究正在不断深入。HBV与肝癌发病机理的报道较多,本文就HCV与肝癌发病机理研究进展作一简要论述。丙型肝炎病毒是输血后肝炎及散发性非甲非乙型肝炎的主要致病病原体。1989年美国的Choo等从感染的黑猩猩血液标本中,从100万克隆中仅找到一个
Nearly 20 years of hepatitis B virus (HBV) and the pathogenesis of liver cancer has made great progress. It is generally believed that chronic HBV infection is closely related to the occurrence of primary liver cancer. And in epidemiology, immunopathology and molecular pathology have been confirmed. In recent years, hepatitis C (HCV) or HBV and HCV infection at the same time or separately and the pathogenesis of liver cancer is in-depth research. There are many reports on the pathogenesis of HBV and hepatocellular carcinoma. This article briefly discusses the research progress on the pathogenesis of HCV and hepatocellular carcinoma. Hepatitis C virus is the main causative agent of post-transfusion hepatitis and sporadic non-A non-B hepatitis. In 1989, Choo et al. Found only one out of a million clones of infected chimp blood samples