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目的探讨临朐县人民医院呼吸内科病房患者侵袭性肺部感染的易患因素、临床特征和治疗方法。方法采用回顾性分析的方法对2008-06-2010-06收住呼吸内科确诊68例侵袭性肺部真菌感染的临床资料进行分析。结果在呼吸内科病房中,慢性阻塞性肺病是继发肺部真菌感染的最常见的基础疾病,社会的老龄化,广谱抗生素、低蛋白血症、长期应用糖皮质激素及合并糖尿病是主要的易患因素。肺部真菌感染的临床表现多种多样,确诊需结合痰培养、组织病理学、病原学,以念珠菌属占首位,共45例。结论治疗原发病,合理应用抗生素,尽量减少糖皮质激素的应用,积极的综合治疗有助于提高真菌感染的治愈率。
Objective To investigate the predisposing factors, clinical characteristics and treatment of invasive pulmonary infection in respiratory medicine department of Linyi County People’s Hospital. Methods The clinical data of 68 cases of invasive pulmonary fungal infection admitted to respiratory medicine during 2008-06-2010-06 were analyzed retrospectively. Results Chronic obstructive pulmonary disease (COPD) is the most common underlying disease secondary to fungal pulmonary infection in the respiratory medical ward, and social aging, broad-spectrum antibiotics, hypoproteinemia, long-term use of glucocorticoids and diabetes mellitus are major Susceptible factors. Clinical manifestations of pulmonary fungal infections varied, confirmed with sputum culture, histopathology, etiology, with Candida in the first place, a total of 45 cases. Conclusion The treatment of primary disease, the rational use of antibiotics, to minimize the application of glucocorticoid, a positive comprehensive treatment helps to improve the cure rate of fungal infection.