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口腔粘膜鳞状上皮可形成一主要的结构屏障,防止微生物和毒素的入侵及组织液的丢失。舌背粘膜有其特殊的结构,沟纹舌患者其舌粘膜的保护作用可能有所下降。本文目的是研究这种患者的舌炎症性变化,是否引起具有诊断意义的唾液成分的改变;同时研究唾液中某些抗微生物因于,以检查患者口腔防御功能的下降程度。研究对象为25名沟纹舌患者(10名男性,15名女性),年龄20~30岁,平均25岁;对照组为25名年龄、性别、口腔卫生均相匹配的健康者。病人组与对照组中,无1人有系统性疾患或药物治疗史,均系非吸烟者。
Oral mucosal squamous epithelium can form a major structural barrier to prevent the invasion of microorganisms and toxins and the loss of tissue fluid. Tongue back mucosa has its special structure, groove tongue tongue patients may reduce the protective effect of the tongue. The purpose of this paper is to investigate if changes in the tongue of this patient cause a change in the salivary component of a diagnostic significance and to study the extent to which certain antimicrobials in saliva are due to examine the decline in oral defense in patients. Twenty-five patients with grooved tongue (10 males and 15 females) aged 20-30 years (average 25 years) were enrolled. The control group consisted of 25 healthy subjects with matched age, sex and oral hygiene. None of the patients and controls had a history of systemic disease or drug treatment, all of whom were non-smokers.