1994年,Tayapongsak等提出了一个新奇的想法:在下颌连续性重建时,将自体纤维蛋白胶粘剂(autologous fibrin adhesive,AFA)加入网状骨内。并认为AFA所提供的纤维支架能够促进移植物中骨活性细胞的骨传导作用。自从90年代早期,本文作者已探查了与之相类似但富含特殊浓缩的自体血小板的血浆(platelet rich plasma,PRP),并研究了血小板内所含生长因子与 In 1994, Tayapongsak et al. Proposed a novel idea of ​​adding autologous fibrin adhesive (AFA) to the reticular bone during continuous mandibular reconstruction. It is also believed that the fibrous scaffold provided by AFA can promote the osteoconduction of bone-derived active cells in the graft. Since the early 1990s, the authors of this study have explored platelet-rich plasma (PRP) similar to, but enriched with, specially concentrated platelets and studied the effect of platelet-rich plasma