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目的通过对深圳特区男性不育患者精液常规检测结果分析,了解本地区男性不育精液质量状况及不育的病因,为临床治疗和预防男性不育提供参考依据。方法应用SQIAS-2000精子质量图文分析系统,对2013年08月~2015年05月来本院就诊的男性不育患者2791例的精液量、液化时间、p H值、精子数、精子活力、精子活动率及异常精子等参数进行统计分析。结果参照WHO精液参数判断标准,2791例不育患者中精液常规各项参数结果均处于正常范围的占29.6%(826/2791),一项或多项精液常规参数异常的占70.4%(1965/2791),两组除了精液量和p H值两个参数无差异外,其它参数结果之间差异均有统计学意义(t=10.262~15.723,P<0.01);1965例异常精液标本中,液化时间、活力a级、活力a+b级、活动率、精子数及异常精子分别占64.73%、83.26%、60.71%、46.56%、31.50%和26.16%。结论深圳地区男性不育患者精液常规参数异常情况比较严重,主要表现在精子活力下降、精液液化时间延长和精子活动率降低,是深圳地区男性不育的主要影响原因。
Objective To analyze the results of routine test of sperm in male patients with infertility in Shenzhen Special Economic Zone so as to understand the quality of male infertility and the cause of infertility in this area and provide a reference for clinical treatment and prevention of male infertility. Methods SQIAS-2000 sperm quality graphic analysis system was used to measure the semen volume, liquefaction time, p H value, sperm number, sperm motility, Sperm motility and abnormal sperm and other parameters for statistical analysis. Results According to WHO criteria for semen parameters, the results of routine semen parameters in 2791 infertile patients were all in the normal range (29.6% (826/2791)), and one or more semen parameters were abnormal in 70.4% (1965 / 2791). There was no significant difference between the two groups except the semen volume and p H value (t = 10.262 ~ 15.723, P <0.01). In the 1965 abnormal semen samples, liquefaction Time, vitality a, vitality a + b, activity, sperm count and abnormal sperm accounted for 64.73%, 83.26%, 60.71%, 46.56%, 31.50% and 26.16% respectively. Conclusions The abnormal sperm parameters in male infertility patients in Shenzhen are more serious, mainly due to the decrease of sperm motility, the prolongation of sperm liquefaction and the decrease of sperm motility rate, which are the main reasons of male infertility in Shenzhen area.