皮肤恶性黑素瘤的正确组织学诊断是重要的。以往应用单克隆抗体及免疫过氧化物酶技术在鉴别不能确定的肿瘤团块是否来源于黑素细胞有意义。然而不能区别良性与恶性的黑素细胞皮损。应用Ag NOR 技术区别恶性黑素瘤与良性黑素细胞痣是一种可选用的方法。核仁形成体区(NOR)在细 The correct histological diagnosis of cutaneous malignant melanoma is important. The use of monoclonal antibodies and immunoperoxidase techniques in the past has been shown to be useful in the identification of undefined tumor masses that are derived from melanocytes. However, benign and malignant melanocyte skin lesions cannot be distinguished. The use of the Ag NOR technique to distinguish malignant melanoma from benign melanocytes is an alternative method. Nucleosome formation area (NOR) in fine