在人体呼吸道中寄居着大量的细菌,与呼吸道其他微生物共同参与构成人体固有免疫,形成抵御外界病原侵袭的屏障。这些细菌中包括了呼吸道定植菌,它们寄生在气道中却不致病,不会使宿主产生临床症状,然而这些定植菌并不是简单的寄居于呼吸道中。近年来随着呼吸道微生物检测技术的进步,人们对呼吸道微生物与呼吸道疾病的研究更为深入~([1-2])。越来越多的研究发现,呼吸道定植参与儿童喘息性 Residing in the human respiratory tract with a large number of bacteria, together with other microorganisms in the respiratory tract constitute the body’s innate immunity, the formation of a barrier against the invasion of pathogens. These bacteria include respiratory bacteria, which parasitize the airways without causing disease and do not produce clinical symptoms in the host. However, these bacteria do not simply reside in the respiratory tract. In recent years, with the progress of respiratory microbial detection technology, people are more in-depth study of respiratory microorganisms and respiratory diseases ~ ([1-2]). More and more studies have found that respiratory colonization is involved in wheezing in children