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甲基杀虫脒盐酸盐[34.62%原油,LD_(30)=313.74(雌)和273.10(雄)mg/kg]是毒性较低,对螟虫杀灭效高,但它对繁殖功能的影响少见报道。选用 NIH 小白鼠随机配组,开展高剂量(52.383与45.16ppm)、低剂量(10.45与9.1ppm)及对照组的繁殖试验,为期106天。第一次交配后,母鼠死亡率、受孕率、仔鼠出生存活率、哺育成活率,三组互相比较差异不显著(P>0.05)。第二次交配后,母鼠死亡率、受孕率及仔鼠哺育存活率,三组互相比较差异不显著(P>0.05),但仔鼠出生存活率差异非常显著(P<0.01)。全实验中母鼠体重增减率,三组相互比较差异不显著(P>0.05)。上述试验资料表明,甲基杀虫脒盐酸盐对 NIH 小白鼠的繁殖功能无明显影响。对于第二次交配所产仔鼠的出生存活率,三组互相比较有非常显著性差异,原因何在,有待深入研究。
Methyl chlordimeform hydrochloride [34.62% crude, LD 30 = 313.74 (female) and 273.10 (male) mg / kg] is less toxic and has a high killing effect on the stem borer but its effect on reproductive performance Rarely reported. NIH mice were randomly assigned to high-dose (52.383 and 45.16ppm), low-dose (10.45 and 9.1ppm) and control groups of breeding experiments for a period of 106 days. After mating for the first time, there was no significant difference between the three groups (P> 0.05). There was no significant difference in maternal mortality, pregnancy rate, birth survival rate and feeding survival rate among the three groups. After mating for the second time, there was no significant difference between the three groups (P> 0.05). However, there was a significant difference in birth survival rate between the three groups (P <0.01). The weight loss rate of maternal rats in the whole experiment was not significantly different among the three groups (P> 0.05). The above experimental data show that methyl chlordimeform hydrochloride NIH mice reproductive function had no significant effect. For the second generation of offspring born offspring survival rate, the three groups compared with each other very significant differences, the reason why, pending further study.