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将30例全麻病人随机分为两组,静脉推入双氢埃托菲及卡肌宁后,分别推注异丙酚2.5mg/kg或硫喷妥钠5mg/kg,2分钟后行气管内插管,并观察插管前、插管即刻、插管后1、3、5分钟时的血压、心率变化。结果显示:插管即刻及插管后1、3分钟时,硫喷妥钠组的血压与入室时相比稍有上升,而异丙酚组则低于入室值,两组间有非常显著性差异(P<0.01)。两组间的心率变化无显著性差异。结论:异丙酚抑制插管后的心血管反应明显优于硫喷妥钠。
Thirty patients with general anesthesia were randomly divided into two groups. After intravenous injection of dihydroetorphine and carbenicillin, propofol 2.5 mg / kg or thiopental 5 mg / kg were injected respectively, followed by two minutes Endotracheal intubation, and observe the intubation, intubation immediately after intubation 1,3,5 minutes after the blood pressure, heart rate changes. The results showed that immediately after intubation and 1, 3 minutes after intubation, the blood pressure in thiopental group slightly increased compared with that at entry, while the propofol group was lower than the entry value, with significant difference between the two groups Difference (P <0.01). There was no significant difference in heart rate between the two groups. Conclusions: Propofol inhibits cardiovascular responses significantly better than thiopental after intubation.