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采用溶栓疗法治疗 32例急性脑梗塞患者 ,并与用常规方法治疗者进行对照 ,观察两组疗法对白细胞介素 1β (IL - 1β)、白细胞介素 6 (IL - 6 )及肿瘤坏死因子 (TNF-α)的影响 ,并对其疗效进行分析。结果显示 ,溶栓组 IL- 1β、IL- 6及 TNF- α在溶栓后 2小时及 6小时明显下降 ,与其疗效及预后显著相关 ;与对照组比较 ,其欧洲卒中评分 (ESS)和 3个月后的每日生活活动 (Bathal)指数明显改善。提示溶栓组的近、远期效果均明显优于对照组。
Thirty - two patients with acute cerebral infarction were treated by thrombolytic therapy and compared with those treated by conventional methods. The effects of two therapies on interleukin - 1β, interleukin - 6 (IL - 6) and tumor necrosis factor (TNF-α), and its efficacy analysis. The results showed that the levels of IL-1β, IL-6 and TNF-α in the thrombolytic group decreased significantly 2h and 6h after thrombolysis, which were significantly correlated with the curative effect and prognosis. Compared with the control group, the European stroke scores (ESS) and 3 Months after the Bathal index improved significantly. Tip thrombolytic group near and long-term results were significantly better than the control group.