遗传性多发性骨软骨瘤，患者大多有家族史，但相继五代发病者十分罕见。我院收治１例，追问其家族史，近五代中７人患有本病，现报告如下。患者男，３岁，出生后６个月其父母发现患儿左肩背部有一花生米大小包块，渐进性增大，无疼痛，未予治疗。近半年，患儿出现无痛性跛... In patients with hereditary multiple osteochondromas, most patients have a family history, but the onset of five consecutive generations is very rare. In our hospital, 1 patient was admitted and his family history was followed. Seven people in the last five generations had this disease. The report is as follows. The patient, male, 3 years old, 6 months after birth, his parents found that there was a peanut-sized mass in the left shoulder of the patient, which gradually increased without pain and was not treated. In the past six months, children have experienced painless spasms.