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薄芝糖肽注射液是从薄树芝干燥菌丝体粉末中提取的制剂,临床主要用于肿瘤辅助治疗。本文报告了1例甲状腺右侧叶肿瘤患者在静脉滴注薄芝糖肽注射液8min后,出现全身潮红、呼吸急促、血压下降、面色青紫、大小便失禁、全身强直等过敏性休克症状。立即停止静脉滴注薄芝糖肽注射液,给予吸氧、心电监护,静脉注射地塞米松10mg、异丙嗪25mg,症状无改善,继而出现牙关紧闭、病情加重,给予气管插管,再次静脉注射地塞米松10mg,肌内注射异丙嗪25mg。30min后,患者意识恢复、面色转红、口唇红润,体温36.6℃,心率114/min,呼吸26次/min,血压92/55mmHg,血氧饱和度(SpO_2)0.93。50min后,生命体征平稳,心率100/min,呼吸20次/min,血压133/79mmHg,SpO_2 0.98。
Bozhi Glycopeptide Injection is a preparation extracted from the dried Mycelium of Gracilaria lemaneiformis, which is mainly used for the adjuvant treatment of tumors. This article reports a case of right thyroid tumor in patients with intravenous infusion of thin Zhi Tang peptide injection 8min after the emergence of body flushing, shortness of breath, decreased blood pressure, looking bruising, incontinence, tonic and other anaphylactic shock symptoms. Immediately stop intravenous infusion of thin glycopeptide injection, given oxygen, ECG monitoring, intravenous injection of dexamethasone 10mg, promethazine 25mg, no improvement in symptoms, followed by trismus, exacerbations, given tracheal intubation, Again intravenous dexamethasone 10mg, intramuscular injection of promethazine 25mg. After 30 minutes, the patient’s consciousness recovered, the complexion turned red, the lip was rosy, the body temperature was 36.6 ℃, the heart rate was 114 / min, the breath was 26 times / min, the blood pressure was 92/55 mmHg and the spO2 was 0.93.50min, Heart rate 100 / min, breathing 20 times / min, blood pressure 133 / 79mmHg, SpO_2 0.98.