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目的探讨分析埃索美拉唑在消化性溃疡治疗中的临床应用价值。方法 68例消化性溃疡患者,随机分为对照组和实验组,各34例。实验组患者给予埃索美拉唑、阿莫西林、克林霉素治疗,对照组患者给予奥美拉唑联合阿莫西林、克林霉素治疗,对比两组患者的临床疗效及不良反应情况。结果实验组患者总有效率达97.06%,不良反应发生率为2.94%;对照组患者总有效率为85.29%,不良反应发生率为17.65%,两组比较差异具有统计学意义(P<0.05)。结论埃索美拉唑治疗消化性溃疡,起效迅速、安全,不良反应轻微,值得临床推广应用。
Objective To investigate the clinical value of esomeprazole in the treatment of peptic ulcer. Methods 68 cases of peptic ulcer patients were randomly divided into control group and experimental group, 34 cases in each. Patients in the experimental group were treated with esomeprazole, amoxicillin and clindamycin, while those in the control group were treated with omeprazole combined with amoxicillin and clindamycin. The clinical efficacy and adverse reactions of the two groups were compared . Results The total effective rate was 97.06% and the adverse reaction rate was 2.94% in the experimental group. The total effective rate was 85.29% in the control group and 17.65% in the experimental group, with significant difference between the two groups (P <0.05) . Conclusion Esomeprazole treatment of peptic ulcer, rapid onset, safety, minor adverse reactions, it is worth promoting the clinical application.