缺血性卒中后的次级预防及病情的进展评估

来源 :世界核心医学期刊文摘(神经病学分册) | 被引量 : 0次 | 上传用户:nightwish110
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Background and Abstract:Objective: An optimal management of vascular risk factors, associated with antithrombotic drugs and carotid surgery when appropriate, reduces the risk of a new vascular event after stroke. Although secondary prevention is not optimal in many patients in practice, the question of whether there is an improvement over time remains unanswered. The aim of our study was to test the hypothesis that secondary prevention measures after cerebral ischemia improve over time. Method: We included 123 consecutive patients in 1994, and 125 consecutive patients in 2002, who were admitted to a neurological department for any reason and had had an episode of cerebral ischemia less than 6 years earlier. We compared the groups for the management of arterial hypertension, hypercholesterolemia, diabetes mellitus and smoking. We recorded the values of blood pressure, biological parameters, and presence of antithrombotic therapy, lipid- lowering and anti- hypertensive drugs. Whether patients were properly treated or not, was determined by a comparison between their current treatment and guidelines available when recruited. Results: Prevention was not optimal in 96 of 123 (78% ) patients in 1994, and in 77 of 125 (62% ) in 2002. Vascular risk factors were better identified and managed in 2002 than in 1994, especially for hypercholesterolemia. Antithrombotic therapies, statins and anti- hypertensive drugs, except calcium channel blockers, were more often used in 2002. The proportion of patients in whom arterial hypertension and hypercholesterolemia were identified was higher in 2002, but the proportion of patients identified as diabetics remained stable. However, the proportion of patients with blood pressure > 140/90 mmHg, glycemia ≥ 126 mg/dl, total cholesterol level ≥ 240 mg/dl, or being current smokers, were significantly lower in 2002 than in 1994. Conclusion: Although most of patients with previous cerebral ischemia did not receive an optimal management of their risk factors in 2002, there was an improvement over an 8- year period. Background and Abstract: Objective: An optimal management of vascular risk factors, associated with antithrombotic drugs and carotid surgery when appropriate, reduces the risk of a new vascular event after stroke. Although secondary prevention is not optimal in many patients in practice, the question of The aim of our study was to test the hypothesis that secondary prevention measures after cerebral ischemia improve over time. Method: We included 123 consecutive patients in 1994, and 125 consecutive patients in 2002, who were admitted to a neurological department for any reason and had an episode of cerebral ischemia less than 6 years earlier. We compared the groups for the management of arterial hypertension, hypercholesterolemia, diabetes mellitus and smoking. We recorded the values ​​of blood pressure, biological parameters , and presence of antithrombotic therapy, lipid- lowering and antihypertensive drugs. Whether pat ients were properly treated or not, was determined by a comparison between their current treatment and guidelines available when recruited. Results: Prevention was not optimal in 96 of 123 (78%) patients in 1994, and in 77 of 125 (62%) in 2002. Vascular risk factors were better identified and managed in 2002 than in 1994, especially for hypercholesterolemia. Antithrombotic therapies, statins and anti-hypertensive drugs, except calcium channel blockers, were more often used in 2002. The proportion of patients in whom arterial hypertension and hypercholesterolemia were identified as higher in 2002, but the proportion of patients identified as diabetics remained stable. However, the proportion of patients with blood pressure> 140/90 mmHg, glycemia ≥ 126 mg / dl, total cholesterol level ≥ 240 mg / dl , or being current smokers, were significantly lower in 2002 than in 1994. Conclusion: Although most of patients with previous cerebral ischemia did not receive an optimal management of th eirrisk factors in 2002, there was an improvement over an 8-year period.
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