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红景天甙元腹腔注射100mg/kg和200mg/kg对戊巴比妥钠入睡时间和催眠作用时间均无明显影响,300mg/kg可显著缩短戊巴比妥钠入睡时间和延长催眠作用时间,对电惊厥无保护作用,对常压缺氧所致动物死亡时间无明显影响,对高温所致动物死亡数无明显影响,对角叉菜胶所致踝关节肿胀有抑制作用,但局部用药对巴豆油所致耳部肿胀无抑制作用。红景天甙元给家兔静脉注射60mg/kg和150mg/kg,给大鼠腹腔注射200mg/kg,对胆汁排泌均无明显影响。离体实验,红景天甙元12.5×10~(-1)mg/ml可使大鼠离体回肠平滑肌张力降低,收缩幅度变小;25×10~(-1)mg/ml对Ach和BaCl_2引起的回肠平滑肌收缩均有抑制作用。
The intraperitoneal injection of 100mg/kg and 200mg/kg of Rhodiola rosea had no significant effect on the sleep time and hypnotic action time of pentobarbital sodium. 300mg/kg can significantly shorten the sleep time and extend the hypnotic action time of pentobarbital sodium. There was no protection against electroconvulsions, no significant effect on the time of animal death caused by normobaric hypoxia, no significant effect on the number of animal deaths caused by high temperature, and inhibition of ankle swelling caused by carrageenan, but topical application Croton oil caused no swelling in the ears. Intravenous injection of 60 mg/kg and 150 mg/kg intravenously to the rabbits of Rhodiola rosea was given to the rats by intraperitoneal injection of 200 mg/kg with no significant effect on bile excretion. In vitro experiments, Rhodiola aurantium 12.5 × 10 -1 mg/ml can reduce the tension of rat ileum smooth muscle and reduce the contraction amplitude; 25×10 -1 mg/ml to Ach and BaCl 2 induced ileal smooth muscle contraction are inhibited.