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[目的]观察逍遥散联合美沙拉嗪肠溶片治疗溃疡性结肠炎疗效。[方法]使用随机平行对照方法,将80例门诊患者按随机数字表法分为两组。对照组40例美沙拉嗪肠溶片1g/次,5次/d。治疗组40例逍遥散(炙甘草7g,柴胡16g,枳壳14g,党参22g,木香16g),1剂/d,水煎200mL,早晚温服;西医治疗同对照组。连续治疗12d为1疗程。观测临床症状、结肠黏膜状态、C-反应蛋白(CRP)、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈22例,有效16例,无效2例,总有效率95.00%。对照组痊愈15例,有效12例,无效13例,总有效率67.50%。治疗组疗效优于对照组(P<0.05)。两组CRP值均有改善(P<0.01),治疗组优于对照组(P<0.01)。[结论]逍遥散联合美沙拉嗪肠溶片治疗溃疡性结肠炎疗效显著,值得推广。
[Objective] To observe the efficacy of Xiaoyao San combined mesalazine enteric-coated tablets in the treatment of ulcerative colitis. [Method] Using randomized parallel method, 80 outpatients were divided into two groups according to random number table method. Control group 40 cases Mesalazine enteric-coated tablets 1g / time, 5 times / d. Treatment group 40 Xiaoyao San (Baked Licorice 7g, Bupleurum 16g, Citrus aurantium 14g, Codonopsis 22g, woody 16g), 1 / d, decoction 200mL, morning and evening warm clothes; Western medicine treatment with the control group. Continuous treatment of 12d for a course of treatment. Clinical symptoms, colonic mucosal status, C-reactive protein (CRP), adverse reactions were observed. Treatment of a course of treatment to determine the efficacy. [Result] In the treatment group, 22 cases were cured, 16 cases were effective, 2 cases were ineffective, and the total effective rate was 95.00%. The control group recovered 15 cases, 12 cases were effective, 13 cases were ineffective, the total effective rate was 67.50%. The treatment group was better than the control group (P <0.05). Both CRP values were improved (P <0.01), and the treatment group was better than the control group (P <0.01). [Conclusion] Xiaoyao San combined mesalazine enteric-coated tablets for the treatment of ulcerative colitis significant effect, it is worth promoting.