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侵袭性念珠菌病是重症监护病房(ICU)威胁生命的严重并发证。然而,由于念球菌病的诊断困难,治疗常不及时甚至未得到治疗。念珠菌的危险因素包括:中心静脉装置,顽固性消化道穿孔,急性胰腺炎或脾切除术后,肾功能不全或血液透析。伴有以上高危因素患者发生全眼炎或视网膜炎,伴有其它念珠菌病症状,尤其是当二个以上部位检出菌落,或接受高危手术(近期腹部手术或复发性消化逍穿孔),即使无临床症状,可试行抗念珠菌治疗。有助于念珠菌病诊断的病原学资料包括:分离部位,阳性次数,非相邻部位,菌落密度和细菌种类。从血培养或通常无菌的体液,烧伤患者的创面或脓肿中分离到念珠菌;菌落指数>0.5或矫正菌落指数>0.4,或检出副热带念珠菌时,应立即开始抗念珠菌治疗。
Invasive candidiasis is a serious and life-threatening card in ICU. However, due to the diagnosis of cryptococcosis, treatment is often not timely or even untreated. Risk factors for Candida include: central venous devices, refractory gastrointestinal perforation, acute pancreatitis or splenectomy, renal insufficiency or hemodialysis. Patients with all the above risk factors have all-ophthalmia or retinitis, with other symptoms of candidiasis, especially when colonies are detected in more than two sites or undergoing high-risk surgery (recent abdominal surgery or recurrent digestion), even though No clinical symptoms, try anti-Candida treatment. Pathogenic data that contributes to the diagnosis of candidiasis include: site of separation, number of positives, non-contiguous site, colony density, and bacterial species. Candida is isolated from blood cultures or normally sterile body fluids, wounds or abscesses from burns; colony index> 0.5 or colony index> 0.4, or Candida tropicalis, should be started immediately.