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对52例慢性阻塞性肺疾病(COPD)患者进行床旁最大吸气流速(MIFR)监测。结果:COPD急性加重期MIPR较缓解期明显降低(P<0.05),后者较正常人MIFR亦显著降低(P<0.05);急性加重期伴CO_2潴留者MIFR值低于无CO_2潴留者(P<0.05)。MIFR与PaCO_2呈负相关(r=-0.62,P<0.005),与最大通气量(MVV)呈正相关(r=0.61,P<0.005),直线回归方程分别为:Y(PaCO_2)=67.4-14.3MIFR(L/s),Y(MVV)=9.8+19.3MIFR(L/s)。提示:MIFR是准确反映肺功能损害程度的可靠指标,并能提示预后,对及时发现吸气肌疲劳,进行合理治疗有指导作用。
52 cases of chronic obstructive pulmonary disease (COPD) patients bedside maximum inspiratory flow rate (MIFR) monitoring. Results: The MIPR in acute exacerbation of COPD was significantly lower than that in remission (P <0.05), and the latter was significantly lower than that in normal subjects (P <0.05). The MIFR of patients with exacerbation of COPD was lower than that without CO_2 Retention (P <0.05). MIFR was negatively correlated with PaCO_2 (r = -0.62, P <0.005), and positively correlated with MVV (r = 0.61, P <0.005). The linear regression equations were: Y (PaCO 2) = 67.4-14.3 MIFR (L / s), Y (MVV) = 9.8 + 19.3 MIFR (L / s). Tip: MIFR is a reliable indicator of lung function damage accurately reflect the degree and prognosis, timely detection of inspiratory muscle fatigue, a reasonable guide to the treatment.