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应用各种镇痛试验法,探讨了经口给予麻黄附子细辛汤提取剂的镇痛效果。结果:①醋酸扭体法:剂量为250mg/kg时明显抑制;②甲醛试验法:1000mg/kg时明显抑制第1相;③甩尾法:2100mg/kg时有明显的抗侵害耐受作用;④压尾法(正常):1400mg/kg时有明显的抗侵害耐受作用;⑤压尾法(反复寒冷应激负荷,RCS):350、700、1400mg/kg
A variety of analgesic tests were used to investigate the analgesic effect of ephedra aconite astigmatism extract. RESULTS: 1 The acetic acid writhing method was obviously inhibited when the dose was 250 mg/kg; 2 Formaldehyde test method: the first phase was obviously inhibited at 1000 mg/kg; 3 The tail flicking method: There was obvious anti-invasive and tolerance-resistance at 2100 mg/kg; 4Fat tailing method (normal): Significant anti-invasion and tolerance resistance at 1400 mg/kg; 5 Tail-tailing method (repetitive cold stress load, RCS): 350, 700, 1400 mg/kg