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据猜想．艾滋病患者对碘胺药物的副作用反应率较高，原因系其对磺胺活性代谢物敏感性增高所致。针对此假设，作者研究观察了磺胺活性代谢物对人类免疫缺陷病毒（HIV）感染的周围血单核细胞（PBMCs-的药物毒性动力学。方法用磺肢甲基异唑（SMZ）的羟基胺（浓度由0~400μm）与被H
It is supposed. AIDS patients on the side effects of iodine drug response rate is higher, due to its increased sensitivity to sulfa metabolites. In response to this hypothesis, the authors investigated the toxicokinetics of sulfonamide active metabolites against human immunodeficiency virus (HIV) infected peripheral blood mononuclear cells (PBMCs-). Methods Hydroxylamine (Concentration from 0 ~ 400μm) and was H