我院1991～1993年共收治缓症链球菌感染332例，其中脑实质损害为突出表现的急性感染性中毒性脑病11例，现报告如下。临床资料本组病例中，男8例，女3例；年龄15～46岁，平均27．2岁；发病至就诊时间1～3天。在院外误诊为上呼吸道感染9例，流行性出血热2例。入院时体温39～41．5 Our hospital from 1991 to 1993 were treated in 332 cases of Streptococcus mutans infection, in which brain parenchymal damage was the prominent manifestations of acute infectious toxic encephalopathy in 11 cases, are as follows. Clinical data of this group of patients, 8 males and 3 females; aged 15 to 46 years, mean 27.2 years; onset to treatment time of 1 to 3 days. In the hospital misdiagnosed as upper respiratory tract infection in 9 cases, 2 cases of epidemic hemorrhagic fever. Admission temperature 39 ~ 41.5