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Nature Medicine近期发表了南京医科大学药学院朱东亚教授等题为“阻断缺血诱导的nNOS与PSD95相互作用治疗脑缺血损伤”(Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95)的论文。该研究发现了一个治疗脑卒中的新药物作用靶点,研究了一种有效且能避免副作用的小分子药物。该杂志社特邀该领域的科学家为此发表评论,称小分子药物ZL-006的出现让我们看到了脑卒中等神经系统疾病治疗的新曙光。
Nature Medicine recently published Professor Zhu Dongya of Nanjing Medical University School of Medicine titled "Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with (blockade of ischemic-induced interaction of nNOS and PSD95) PSD-95) thesis. The study found a new drug target for stroke treatment and investigated a small molecule drug that is effective and avoids side effects. The magazine invited scientists in the field to comment on the issue and said the advent of the small molecule drug ZL-006 shows us a new dawn in the treatment of neurological diseases such as stroke.