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目的探讨小剂量低分子肝素钙在慢性阻塞性肺疾病中的应用。方法将189例随机分为常规治疗组90例采取常规治疗和肝素组98例采取常规治疗联合肝素治疗,观察两组临床疗效。结果常规治疗组总有效率82.22%,肝素组总有效率95.91%,两组总有效率比较P<0.05,差异有统计学意义。结论治疗慢性阻塞性肺疾病时应积极认识到本病的血液流变学异常,应用小剂量低分子肝素钙可以达到改善肺部微循环、改善肺泡通气、促进炎症的恢复、促进痰液的排出,促进疾病康复。
Objective To investigate the application of low-dose low molecular weight heparin calcium in chronic obstructive pulmonary disease. Methods A total of 189 patients were randomly divided into conventional treatment group (n = 90) and conventional heparin treatment group (n = 98). Conventional heparin treatment was used to observe the clinical curative effect of the two groups. Results The total effective rate was 82.22% in the conventional treatment group and 95.91% in the heparin group. The total effective rate in the two groups was significantly lower than that in the control group (P <0.05). The difference was statistically significant. Conclusion The treatment of chronic obstructive pulmonary disease should be actively aware of the disease, abnormal blood rheology, the application of low-dose low-molecular-weight heparin calcium can improve lung microcirculation, improve alveolar ventilation, promote inflammation recovery, and promote sputum discharge , Promote disease rehabilitation.