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文献报道疟原虫存在多胺合成代谢的鸟氨酸脱羧酶,还报道该酶的抑制剂二氟甲基鸟氨酸对疟原虫有抑制作用.我们在研究疟原虫多胺代谢时亦观察到人恶性疟Fcc_1株疟原虫存在鸟氨酸脱羧酶活力,并用该酶的抑制剂放线菌酮(Cycloheximide)
Reported in the literature of polyamines synthesis ornithine decarboxylase synthesis of polyamines, also reported that the inhibitor of the enzyme difluoromethylornithine on Plasmodium inhibition.We also observed in the study of Plasmodium polyamine metabolism The ornithine decarboxylase activity of falciparum malaria parasite Fcc_1 was observed. Cycloheximide inhibitor,