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研究了由乙酸乙烯酯经氯化、水解,与硫脲进行环化反应制备2-氨基噻唑的工艺路线,并采用正交实验确定了最佳工艺条件。
The process of preparing 2-aminothiazole from vinyl acetate by chlorination, hydrolysis and cyclization with thiourea was studied. The optimum technological conditions were determined by orthogonal experiments.