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本文用酶联免疫吸附分析的方法测定了40例正常人,99例甲状腺疾病病人血清中的促甲状腺素受体抗体。正常人S/N 比值为1.00±0.12(M±SD).促甲状腺素受体抗体在22/26例未治疗的Graves ’甲亢中阳性。平均S/N 比值为1.66±0.59(p<0.05).40例经治疗后,病情趋于缓解的病人,S/N 比值为1.05±0.49(p>0.05)。在甲功正常的桥本甲炎中,5/16例促甲状腺素受体抗体阳性。平均S/N 比值为1.24±0.79(p>0.05)。4/8例甲低促甲状腺素受体抗体阳性。
In this paper, the enzyme-linked immunosorbent assay method was used to determine thyrotropin-receptor antibody in 40 normal subjects and 99 thyroid disease patients. The normal S / N ratio was 1.00 ± 0.12 (M ± SD). The thyrotropin-receptor antibody was positive in 22/26 untreated Graves’ hyperthyroidism. The mean S / N ratio was 1.66 ± 0.59 (p <0.05), and the S / N ratio was 1.05 ± 0.49 (p> 0.05) in 40 patients whose disease tended to be alleviated. In Hashimoto’s thyroiditis, 5 of the 16 thyrotropin-receptor antibodies were positive. The mean S / N ratio was 1.24 ± 0.79 (p> 0.05). 4/8 cases of hypothyroidism with thyroid hormone receptor antibody positive.