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目的探讨阿昔洛韦治疗小儿水痘的临床疗效。方法选取儿科2012年5月-2014年5月被确诊的水痘患儿200例,随机分为对照组和治疗组,每组100例。对照组给予利巴韦林治疗,治疗组给予阿昔洛韦治疗,观察两组患儿退热时间、停止出现新发皮疹时间、疱疹基本结痂时间。结果治疗组在退热时间、停止出现新发皮疹时间及疱疹基本结痂时间均优于对照组,统计学上差异有显著性(P<0.05)。结论阿昔洛韦治疗水痘,可迅速控制病情,与利巴韦林比较,退热时间、疱疹结痂时间均明显缩短,而且药物性能安全,可作为治疗水痘的首选药物。
Objective To investigate the clinical efficacy of acyclovir in the treatment of chickenpox in children. Methods A total of 200 children with chickenpox diagnosed in pediatrics from May 2012 to May 2014 were randomly divided into control group and treatment group with 100 cases in each group. The control group was treated with ribavirin. The treatment group was treated with acyclovir. The antipyretic time of the two groups was observed, the time of newly developed rash, the time of basic scab of herpes were stopped. Results The treatment group in the antipyretic time, stop the emergence of new rash time and the basic crusting herpes time are better than the control group, the difference was statistically significant (P <0.05). Conclusion Aciclovir treatment of chickenpox, can quickly control the disease, compared with ribavirin, antipyretic time, herpes scab time were significantly shorter, and the drug performance is safe, can be used as the treatment of chicken pox drug of choice.