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重力场流分离是技术和原理上最简单的一种场流分离技术,利用重力场作为外加场,应用范围广泛,常用于分离表征粒径几微米到几百微米的颗粒及生物样品。因其操作简单、易于维护、成本低、分析时间短、条件温和等优点受到越来越多的关注。本文对重力场流分离技术的原理、应用及发展现状进行总结,并重点介绍了其在微米颗粒及生物样品分离中的应用,同时对各种检测方法进行系统全面的比较,并对其发展前景进行展望。
Gravitational field flow separation is the simplest technology and principle of a field flow separation technology, the use of gravity field as applied field, a wide range of applications, commonly used in the separation and characterization of particle size of several microns to hundreds of microns of particles and biological samples. Because of its simple operation, easy to maintain, low cost, short analysis time, mild conditions and other advantages by more and more attention. This paper summarizes the principle, application and current situation of gravity field flow separation technology, and focuses on its application in the separation of microparticles and biological samples. At the same time, a systematic and comprehensive comparison of various detection methods is carried out, and its development prospects Prospects.