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乙醇可促使硫酸吗啡缓释胶囊加速释放美国Ligand制药公司已经加强了硫酸吗啡缓释胶囊(商品名:Avinza)说明书中的警戒内容:服用硫酸吗啡缓释胶囊的患者不能饮酒。因为乙醇可使吗啡缓释胶囊快速释放并能吸收潜在的致死剂量吗啡。另外,患者也不能联用含有乙醇的处方或非处方药。
Ethanol promotes accelerated release of morphine sulfate sustained release capsules Ligand Pharmaceuticals USA has stepped up the precautionary statements in the manual of morphine sulfate sustained release capsules (trade name: Avinza): Patients taking morphine sustained-release capsules can not drink alcohol. Because ethanol allows rapid release of morphine sustained-release capsules and absorbs potentially lethal doses of morphine. In addition, patients should not be given prescribing or over-the-counter medications that contain ethanol.