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4.治疗风湿病的药物近年来,抗风湿病药物的品种有显著的增加。在这许多新的药物中,我们在此只能提一些已经进入药物市场的品种。苯氟布洛芬(Flurbiprofen,38a)是脂肪酸芳香基取代物中的一个代表,对它的药理作用曾作了广泛的研究。通过前列腺素合成的抑制试验而了解到,本品具有强烈的镇痛、退热和消炎作用。由于它能抑制血小板的聚集,所以33a具有防治血栓的作用。此外,它能够影响钙-代谢,因而亦具有抗转移的作用。本品经人体口服后迅速被吸收,其中约99％与血浆蛋白结合(给药后60～90分钟血
4. Treatment of rheumatism drugs In recent years, the varieties of anti-rheumatic drugs have significantly increased. Among the many new drugs we can only mention here are varieties that have entered the pharmaceutical market. Flurbiprofen (38a), a representative of fatty acid aryl substituents, has been extensively studied for its pharmacological effects. By prostaglandin synthesis inhibition test and learned that this product has a strong analgesic, antipyretic and anti-inflammatory effect. Because it can inhibit the aggregation of platelets, so 33a has the effect of prevention and treatment of thrombosis. In addition, it can affect calcium-metabolism and therefore also has anti-metastatic effects. This product is quickly absorbed by the human oral administration, of which about 99% and plasma protein binding (60 to 90 minutes after administration of blood