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为探讨中心性浆液性视网膜脉络膜病变(简称中浆)的发病机理,对37例中浆患者和30名正常人的部分免疫机能用单向琼脂扩散法和形态学检查法进行测定。结果发现中浆患者的T淋巴细胞转化率及E—玫瑰花结形成率均较正常对照组显著降低,血清IgG、IgA亦较正常对照组明显下降,而血清IgM则变化不显著。提示中浆发病与机体免疫功能低下有关,临床上不宜用糖皮质激素治疗中浆。
In order to explore the pathogenesis of central serous chorioretinopathy (hereinafter referred to as pulp), the immune function of 37 cases of moderate pulp and 30 normal persons were determined by one-way agar diffusion method and morphological examination. The results showed that the T lymphocyte transformation rates and the rate of formation of E-rosette were significantly lower in the middle-aged patients than those in the normal control group. Serum IgG and IgA levels were also significantly lower than those in the normal control group, while serum IgM did not change significantly. Tip of the incidence of pulp and immune function related to low, clinically not suitable glucocorticoid in the treatment of pulp.