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作者报道了27例骨髓移植(BMT)后肺部霉菌感染(PFI),均小于21岁。19例经尸检证实,8例经肺活检或痰血培养等法证实。占全部BMT319例的9%病原菌:曲菌21例(78%)、念珠菌7例(26%)、毛霉菌3例(11%)、孢子菌1例(4%);混合霉菌感染5例(19%;曲菌并念珠菌4例、曲菌伴毛霉菌1例)、11例(41%)尚合并病毒感染(巨细胞病毒7例、流感病毒2例、泡疹病毒2例);同时合并有细菌感染(G~+菌16例、G~-菌6例)。全部病例胸片皆异常。BMT初期:纵隔或肺门淋巴结肿大2例、胸膜渗出或增厚8例;进展期(直至PFI前):单侧浸润14例(52%)、
The authors reported pulmonary mold fungal infection (PFI) in 27 patients with bone marrow transplantation (BMT), both less than 21 years old. 19 cases confirmed by autopsy, 8 cases of lung biopsy or sputum blood culture and other methods confirmed. 9% of pathogenic bacteria accounted for 9% of BMT319 cases: 21 cases (78%) of Aspergillus, 7 cases of Candida (26%), 3 cases of Mucor (11%) and 1 case of sporotia (19%, 4 strains of Aspergillus and Candida, 1 case of Aspergillus and Mucor), and 11 cases (41%) were still infected with virus (Cytomegalovirus 7, Influenza 2 and Herpes zoster 2). At the same time with bacterial infection (G ~ + 16 cases, G ~ - 6 cases). All cases were abnormal chest X-ray. Initial stages of BMT: mediastinal or hilar lymphadenopathy in 2 cases, pleural effusion or thickening in 8 cases; advanced stage (until PFI): unilateral infiltration in 14 cases (52%),