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近年来,作者用雷公藤多甙与中药相配合,治疗肾小球疾病多例,近其疗效尚好,现仅将有肾活检资料的共10例,男7例,女3例,年龄25～48岁,均为慢性发病,肾功能正常,全部病例均在院外作了肾活检,其中IgA肾病2例,系膜增生性肾炎6例,膜增生性肾炎2例。治疗方法:①雷公藤多甙片,每次20mg,每天3次。②中药基本方:茵陈、丹参、土茯苓、苏叶、蝉退、地肤子、布渣叶、北芪、知母。结果,10例中有8例近期缓解(浮肿消退,症状消失,尿常规及肾功能正常,维持3个月以上)2例明显好转(尿常规有少量蛋白及红细胞,其余正常)。雷公藤多甙有较强的抗炎及免疫抑制作用,本治疗提示对于激素治
In recent years, the author with Tripterygium glycosides and Chinese medicine to cooperate in the treatment of glomerular disease in many cases, its efficacy is good, now only a total of 10 cases of renal biopsy data, 7 males and 3 females, aged 25 ~ 48 years old. All of them were chronic onset and had normal renal function. All the patients underwent renal biopsy outside the hospital, including 2 cases of IgA nephropathy, 6 cases of mesangial proliferative glomerulonephritis and 2 cases of membranoproliferative glomerulonephritis. Treatment: ① Tripterygium glycosides tablets, each 20mg, 3 times a day. ② The basic side of traditional Chinese medicine: capillaris, Salvia, Smilax, Su Ye, cicada retreat, Kochia scoparia, Cloth leaves, Beiqi, Anemarrhena. As a result, 8 of 10 patients were recently relieved (edema subsided, symptoms disappeared, and urinary routine and renal function were normal for more than 3 months). 2 cases showed marked improvement (a small amount of protein and erythrocytes were found in urine and the rest were normal). Tripterygium glycosides have a strong anti-inflammatory and immunosuppressive effects, the treatment prompted hormone therapy