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目的探讨舒必利在美施康定治疗癌痛的辅助作用。方法将105例癌痛患者随机分为治疗组53例,对照组52例。两组均给予美施康定口服,治疗组加服舒必利,观察两组的美施康定每日有效量、止痛效果、恶心呕吐发生率等。结果治疗后两组之间美施康定用量、恶心、呕吐发生率有显著差异,止痛疗效无显著差异。结论小剂量舒必利能减少美施康定的有效用量,同时对美施康定所致呕吐具有较好的预防作用。
Objective To investigate the auxiliary effect of sulpiride in the treatment of cancer pain in the United States. Methods 105 patients with cancer pain were randomly divided into treatment group (n = 53) and control group (n = 52). Both groups were given oral administration of Mesangkang, the treatment group plus sulpiride, the two groups were observed daily effective dose, analgesic effect, the incidence of nausea and vomiting. Results After treatment, there was a significant difference in the incidence of nausea and vomiting between the two groups, with no significant difference in analgesic efficacy. Conclusion Small doses of sulpiride can reduce the effective dose of mesyclidine, meanwhile, it has a good preventive effect on vomiting induced by mesyloxacin.