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用β-阻滞剂治疗妊娠期高血压尚有争论。在一项双盲、安慰剂、对照试验中,Rubin等认为用氨酰心安早期抗高血压治疗能够显著地改善胎儿状况,而Walker等称,单用β-阻滞剂还不够,用柳胺苄心定(labetalol)因有α和β阻滞的性质似更为合理。 56例妊娠高血压分为二组,分别用氨酰心安和柳胺苄心定治疗,结果两组血压均被控制,每日平均剂量:氨酰心安为145±48毫克,柳胺苄心定为614±48毫克。柳胺苄心定
Treatment of gestational hypertension with beta-blocker is still debated. In a double-blind, placebo, and controlled trial, Rubin et al. Concluded that early antihypertensive treatment with atenolol significantly improved fetal status, whereas Walker et al. Labetalol seems more reasonable due to the presence of alpha and beta blockers. 56 cases of pregnancy-induced hypertension were divided into two groups, respectively, with atenolol and benazethidine treatment, the results of two groups were controlled blood pressure, the average daily dose: atenolol 145 ± 48 mg, 614 ± 48 mg. Salicylamine Benzidine