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重症肌无力(MG)是一种自身免疫性疾病,主要累及神经-肌肉接头突触后膜烟碱样乙酰胆碱受体,临床表现为肌肉无力和活动后易疲劳。目前研究发现,MG患者可有中枢神经系统受损的症状,表现为多项认知功能的损害。本文就国内外学者对MG患者认知损害的相关研究及其可能的机制进行综述。
Myasthenia gravis (MG) is an autoimmune disease that mainly affects the nicotinic acetylcholine receptor in the postsynaptic neuromuscular junction and its clinical manifestations include muscle weakness and post-exercise fatigue. The current study found that patients with MG may have impaired central nervous system symptoms, manifested as a number of cognitive impairment. This article reviews the domestic and foreign scholars on cognitive impairment in patients with MG and its possible mechanism.