给大鼠经口投与橙皮素(hesperetin)研究了胆汁代谢物的结构。许多黄酮甙显示出在哺乳动物胃肠道中发生微生物水解生成其甙元。因此,经口投与橙皮素估计会产生与相应甙类中得到的相同的代谢物,即广泛分布于柑属植物中的橙皮甙(hesperidin)和新橙皮甙(neohesperidin)。采集大剂量投与橙皮素的大鼠胆汁样本,在Sephadex The rats were orally administered with hesperetin to study the structure of bile metabolites. Many flavonoids have been shown to undergo microbial hydrolysis in the gastrointestinal tract of mammals to produce arsenic. Therefore, oral administration of hesperetin is estimated to produce the same metabolites as those obtained in the corresponding quinones, namely hesperidin and neohesperidin, which are widely distributed in the genus Citrus. Collect large doses of hesperetin-treated rat bile samples in Sephadex