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目的 :研究HSP90α、HSP70在喉癌中的表达与预后的关系。方法 :用免疫组化方法检测 4 6例喉鳞状细胞癌石蜡包埋标本的HSP90α、HSP 70。结果 :喉癌鳞状细胞中HSP90α、HSP70阳性率分别为 6 9 56 %和 6 7 34% ,HSP 90α、HSP70的表达与病理分级和预后有关。结论 :HSP 90α、HSP 70可作为判断患者预后的独立指标。
Objective: To study the relationship between the expression of HSP90α and HSP70 in laryngeal carcinoma and its prognosis. Methods: Immunohistochemistry was used to detect HSP90α, HSP70 in paraffin - embedded specimens of 46 laryngeal squamous cell carcinomas. Results: The positive rates of HSP90α and HSP70 in squamous cell carcinoma of laryngeal squamous cell carcinoma were 69 56% and 67 34%, respectively. The expression of HSP90α and HSP70 were correlated with the pathological grade and prognosis. Conclusion: HSP90α, HSP70 can be used as independent prognostic indicators.