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超临界流体色谱(SFC)是一种很有潜力的色谱分离技术,可以弥补高效液相色谱(HPLC)和气相色谱(GC)在手性对映物分离方面的不足。本文不但介绍了SFC仪器的结构特点,SFC与手性固定相(CSPs)结合在手性分离领域中的应用和最新进展,还对SFC与其它色谱技术的分离效果进行了评价。文献39篇。
Supercritical fluid chromatography (SFC) is a promising chromatographic separation technique that overcomes the limitations of high performance liquid chromatography (HPLC) and gas chromatography (GC) in the separation of chiral enantiomers. This article not only introduces the structural features of SFC instruments, the application and recent progress of combining SFC and chiral stationary phases (CSPs) in the field of chiral separation, but also evaluates the separation effect of SFC and other chromatographic techniques. 39 articles.