在发生溃疡分枝杆菌损害之前,先有创伤的病史已偶有记载,但其直接关系尚不清楚。作者分析了180例因活动性皮肤溃疡而住院的病人发病情况。106例病人的诊断是根据边缘呈潜行性的溃疡,溃疡的排泄物中有抗酸杆菌,组织学特点为含有抗酸杆菌的凝固性坏死。偶有在涂片中见到抗酸杆菌而组织切片中未见抗酸杆菌的病例,如果病理的特点在其他方面是典型的,作者仍认为是溃疡分枝杆菌感染。其中37例的溃疡渗出物或经研碎的活体组织在改良罗氏培养基上置32℃作了培养。其余74例中61例仅根据临床症状而诊断;13例是根据临 Before the occurrence of Mycobacterium ulcerans damage, the history of trauma has been recorded occasionally, but the direct relationship is not clear. The authors analyzed the incidence of 180 hospitalized patients with active skin ulcers. The diagnosis of 106 patients was based on the edge of the ulcer was sneak peptic ulcer excretion of acid-fast bacilli, histological features include acid-fast bacilli coagulation necrosis. Occasional cases of acid-fast bacilli seen in smears and no acid-fast bacilli in histological sections of cases were still considered to be Mycobacterium ulcerans, if pathological features were typical in other areas. Thirty-seven ulcer exudates or pulverized vital tissues were cultured on modified Roche medium at 32 ° C. Of the remaining 74 cases, 61 were diagnosed on the basis of clinical symptoms only; 13 were based on morbidity