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Imipenem/Cilastatin Sodium 是Imipenem 和脱氢肽酶Ⅰ抑制剂(Cilastatin)组成的复方制剂。本文主要研究对其它药剂无效的,由绿脓杆菌等引起的呼吸道感染症,采用本剂治疗的临床效果。受试对象 41例(男29例,女12例),年龄从32岁至88岁,平均年龄69.5岁。给药方法 0.5g、bd,或1.0g、bd。连用时间原则7d 以上。但可视病情适当增减其剂量及用药时间。0.5g、bd 的有20例;1.0g、bd 的有10例。其他:0.5g、0d 及1.0g、0d 各1例。投药期间变更剂量的有9例。连用时间:从3d 至63d,平均为18.4d。其中,3～7d 的有7例,8～14d 的有13例,15
Imipenem / Cilastatin Sodium is a combination of Imipenem and delaying peptidase I inhibitor (Cilastatin). This article mainly studies on other drugs ineffective, caused by Pseudomonas aeruginosa and other respiratory tract infections, the clinical effect of the use of this agent. Subjects in 41 cases (29 males and 12 females), aged from 32 to 88 years old, with an average age of 69.5 years. Method of administration 0.5g, bd, or 1.0g, bd. Use time principle 7d above. However, the appropriate increase or decrease in the visual condition of the dose and medication time. 0.5g, 20 cases of bd; 1.0g, 10 cases of bd. Other: 0.5g, 0d and 1.0g, 0d in 1 case. Dosing during the change in dose in 9 cases. Use time: from 3d to 63d, an average of 18.4d. Among them, 3 ~ 7d in 7 cases, 8 ~ 14d in 13 cases, 15