以2-氨基苯甲酰胺和醛或酮为原料,苯磺酸亚铁为催化剂,采用研磨技术在水相进行反应,高效合成了2,3-二氢-4(1H)-喹唑啉酮。产品结构通过IR,1H NMR,质谱和元素分析进行表征。提出了可能的催化作用机理。该方法具有产率高、操作和后处理过程简便、催化剂能循环使用等优点。 Using 2-aminobenzamide and aldehyde or ketone as raw materials and ferrous benzene sulfonate as catalyst, the reaction was carried out in the aqueous phase by using a grinding technique to synthesize 2,3-dihydro-4 (1H) -quinazolinone . The product structure was characterized by IR, 1H NMR, mass spectrum and elemental analysis. Proposed a possible catalytic mechanism. The method has the advantages of high yield, simple operation and post-treatment process, and recyclable catalyst.