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目的探讨鱼肝油对急性期脑梗塞患者血清维生素Ａ（ＶＡ）和细胞免疫水平的影响及他们之间的相关性。方法用荧光分光光度法和碱性磷酸酶—抗碱性磷酸酶桥联酶标法（ＡＰＡＡＰ），测定血清ＶＡ和周围血Ｔ淋巴细胞亚群ＣＤ３、ＣＤ４、ＣＤ８。结果治疗后血清ＶＡ水平较治疗前明显提高（Ｐ＜０．００１），ＣＤ３、ＣＤ４及ＣＤ４／ＣＤ８有提高趋势，治疗前后血清ＶＡ含量与ＣＤ３、ＣＤ４、ＣＤ４／ＣＤ８均呈显著正相关（Ｐ＜０．００５），治疗后血清ＶＡ含量与ＣＤ８水平呈显著负相关（Ｐ＜０．０５）。结论血清ＶＡ含量与机体免疫功能有关，鱼肝油能提高急性期脑梗塞患者血清ＶＡ水平和细胞免疫功能
Objective To investigate the effects of cod liver oil on serum vitamin A (VA) and cellular immunity in patients with acute cerebral infarction and their correlation. Methods Serum VA and peripheral blood T lymphocyte subsets CD3, CD4 and CD8 were measured by fluorescence spectrophotometry and alkaline phosphatase - alkaline phosphatase (APAAP). Results After treatment, the level of serum VA was significantly increased (P <0.001), while the levels of CD3, CD4 and CD4 / CD8 increased. The serum VA level was positively correlated with CD3, CD4 and CD4 / CD8 before and after treatment <0.005). There was a significant negative correlation between serum VA level and CD8 level after treatment (P <0.05). Conclusions Serum VA levels are related to immune function. Cod liver oil can increase serum VA level and cellular immune function in patients with acute cerebral infarction