蓝色橡皮庖样痣综合征(BRBNS)是一种罕见的多灶型静脉畸形综合征,主要累及皮肤和消化道。传统的治疗方法包括激素治疗、α干扰素治疗、硬化治疗和手术治疗。雷帕霉素治疗之前有少量个案报道。该文作者对4例接受雷帕霉素治疗的BRBNS患儿进行单中心回顾性研究。BRBNS的诊断基 Blue alveolar nevus syndrome (BRBNS) is a rare multifocal venous malformation syndrome, mainly involving the skin and digestive tract. Traditional treatments include hormonal therapy, interferon-alpha therapy, sclerotherapy and surgery. A small number of reported cases of rapamycin have been reported before. The authors performed a one-center retrospective study of 4 BRBNS patients treated with rapamycin. BRBNS diagnostic base