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北京地区第三次光量子血液医疗协作网临床学术报告会于1992年6月26日在中国医学科学院肿瘤医院召开。肿瘤医院范贤俊首先回顾了光动力疗法的研究进展,指出扩大光动力疗法应用于白血病的可能性:应用适宜剂量波长的光辐照血液可直接杀伤血癌细胞;可使淋巴细胞明显升高,促进淋巴细胞致敏因子的释放,继而导致自身免疫反映;可提高白细胞吞噬功能,兴奋免疫系统,激活补体系统;光产物之一F460可能是一种肿瘤杀伤因子;大量被杀伤的白血病细胞波回输到人体后,脾脏对它们产生有效免疫反应而红细胞血浆蛋白等无明显影响。该院对人急性淋巴细胞白血病应用血卟啉(HPD)加长波紫外线治疗的10例中,1例达CR,(?)PR,2(?)无效。肿瘤医院张力军等详细介
The Third Clinical Symposium on Light Quantum Blood Medical Collaboration Network in Beijing was held on June 26, 1992 at the Cancer Hospital of the Chinese Academy of Medical Sciences. Fan Xianjun first reviewed the research progress of photodynamic therapy and pointed out the possibility of expanding photodynamic therapy to leukemia: blood irradiated with a suitable dose of wavelength can directly kill blood cancer cells; lymphocytes can be significantly elevated and promote lymphatic The release of cell sensitization factors, which in turn lead to autoimmune responses; can increase leukocyte phagocytosis, stimulate the immune system, activate the complement system; one of the photoproducts F460 may be a tumor killer; a large number of killed leukemic cells wave back into After the human body, the spleen produced an effective immune response to them but there was no significant effect on the red blood cell plasma protein. Of the 10 patients treated with HPDL in the acute lymphoblastic leukemia, 1 patient achieved CR, (?)PR, and 2(?) were not effective. Tumor Hospital Zhang Lijun et al.